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Purdue Cryo-EM Facility

The Purdue Cryo-EM Facility is a member of the Purdue EM Consortium and a designated Indiana CTSI Core Facility. Our facility is available to Purdue, other academic institutes, and industry users. It provides state-of-the-art instruments and expertise for high resolution structure determination of viruses, larger macromolecular complexes, nano-particles, as well as tomographic visualization of virus-cell interactions by cryo-electron microscopy (cryo-EM) and three-dimensional (3-D) image reconstruction.

Instrument Status

  • Titan Krios G1: Available. Ultrascan will be replaced with a Ceta camera soon. Energy filter tuning should currently only by done by facility staff. Joystick sometimes gets stuck and causes stage drift, TFS is working on a solution.
  • Titan Krios G4: Installation started in July 2020. Enclosure build finished.
  • Talos F200C: Available. K2 has fiber on sensor.